Relationship between L-DOPA-induced reduction in motor and exploratory activity and degree of DAT binding in the rat

Purpose: The present study assessed the influence of L-DOPA administration on neostriatal dopamine (DA) transporter (DAT) binding in relation to motor and exploratory behaviors in the rat.Methods: Rats received injections of 5 mg/kg L-DOPA, 10 mg/kg L-DOPA or vehicle. Motor and exploratory behaviors...

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Principais autores:	Susanne eNikolaus, Markus eBeu, Maria A De Souza Silva, Joseph P. Huston, Hubertus eHautzel, Owen Y Chao, Christina eAntke, Hans-Wilhelm eMüller
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2014-12-01
coleção:	Frontiers in Behavioral Neuroscience
Assuntos:	Exploratory Behavior habituation motor behavior dopamine transporter L-DOPA methylester time-behavior curves
Acesso em linha:	http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00431/full
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