Cardiolipin drives the catalytic activity of GPX4 on membranes: Insights from the R152H mutant
The aim of this study was to examine, in biochemical detail, the functional role of the Arg152 residue in the selenoprotein Glutathione Peroxidase 4 (GPX4), whose mutation to His is involved in Sedaghatian-type Spondylometaphyseal Dysplasia (SSMD). Wild-type and mutated recombinant enzymes with sele...
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| Principais autores: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Elsevier
2023-08-01
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| Series: | Redox Biology |
| Assuntos: | |
| Acceso en liña: | http://www.sciencedirect.com/science/article/pii/S2213231723002070 |
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