High multiplex analysis of the immune microenvironment in bone marrow trephine samples using GeoMX™ digital spatial profiling

Background: To date, studies into the bone marrow (BM) immune microenvironment have been limited due to reliance on the analysis of BM aspirates in which the microenvironmental context is lost. GeoMX™ digital spatial profiling (DSP) is a new technique developed for the analysis of formalin-fixed par...

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Hauptverfasser:	R.M. Koldej, D.S. Ritchie
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2020-03-01
Schriftenreihe:	Immuno-Oncology and Technology
Schlagworte:	bone marrow digital spatial profiling GeoMX immune microenvironment immunohistochemistry trephine
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2590018820300010
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