BRCA1 preserves genome integrity during the formation of undifferentiated spermatogonia

Abstract Undifferentiated spermatogonia, which form shortly after birth, consist of spermatogonial stem cells and progenitor spermatogonia that maintain homeostasis. As the origin of spermatogenesis, undifferentiated spermatogonia must preserve genome integrity. Paradoxically, we demonstrate that ma...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Peng Li, Licun Song, Longfei Ma, Chunsheng Han, Lejun Li, Lin-Yu Lu, Yidan Liu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Springer Nature 2025-05-01
Schriftenreihe:	EMBO Reports
Schlagworte:	Undifferentiated Spermatogonia BRCA1 DNA Damage Repair Genome Integrity
Online-Zugang:	https://doi.org/10.1038/s44319-025-00487-5
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!