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The protective effect of breastfeeding on infant inflammation: a mediation analysis of the plasma lipidome and metabolome

Abstract Background Inflammation has long-term health impacts across the life course. Breastfeeding substantially reduces inflammation risk, but key pathways, including the extent that this is due to protection against early life infection, are poorly understood. We aimed to investigate the relation...

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Main Authors: Satvika Burugupalli, Toby Mansell, Tingting Wang, Alexandra D. George, Sudip Paul, Richard Saffery, Mimi L. K. Tang, Thomas W. McDade, Habtamu B. Beyene, Thy Duong, Peter Vuillermin, Anne-Louise Ponsonby, Barwon Infant Study Investigator Group, David P. Burgner, Peter J. Meikle
Format: Artigo
Language:Inglês
Published: BMC 2025-10-01
Series:BMC Medicine
Subjects:
Breastfeeding
Lipids
Metabolites
Infant nutrition
Inflammation
Online Access:https://doi.org/10.1186/s12916-025-04343-0
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