QR Code

Using Selective Enzymes to Measure Noncanonical DNA Building Blocks: dUTP, 5-Methyl-dCTP, and 5-Hydroxymethyl-dCTP

Cells maintain a fine-tuned balance of deoxyribonucleoside 5′-triphosphates (dNTPs), a crucial factor in preserving genomic integrity. Any alterations in the nucleotide pool’s composition or chemical modifications to nucleotides before their incorporation into DNA can lead to increased mutation freq...

Full description

Saved in:
Main Authors: Éva Viola Surányi, Viktória Perey-Simon, Rita Hirmondó, Tamás Trombitás, Latifa Kazzazy, Máté Varga, Beáta G. Vértessy, Judit Tóth
Format: Artigo
Language:Inglês
Published: MDPI AG 2023-12-01
Series:Biomolecules
Subjects:
dNTP incorporation
dNTP pool
nucleotide hydrolysis
nucleotide analogs
Online Access:https://www.mdpi.com/2218-273X/13/12/1801
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items