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SARS-CoV-2 mutant spectra as variant of concern nurseries: endless variation?

IntroductionSARS-CoV-2 isolates of a given clade may contain low frequency genomes that encode amino acids or deletions which are typical of a different clade.MethodsHere we use high resolution ultra-deep sequencing to analyze SARS-CoV-2 mutant spectra.ResultsIn 6 out of 11 SARS-CoV-2 isolates from...

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Autores principales: Brenda Martínez-González, María Eugenia Soria, Pablo Mínguez, Ramón Lorenzo-Redondo, Llanos Salar-Vidal, Alberto López-García, Mario Esteban-Muñoz, Antoni Durán-Pastor, Pilar Somovilla, Carlos García-Crespo, Ana Isabel de Ávila, Jordi Gómez, Jaime Esteban, Ricardo Fernández-Roblas, Ignacio Gadea, Esteban Domingo, Celia Perales
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2024-03-01
Colección:Frontiers in Microbiology
Materias:
COVID-19
viral quasispecies
ultra-deep sequencing
viral emergence
clade-discordant residues
variant of concern
Acceso en línea:https://www.frontiersin.org/articles/10.3389/fmicb.2024.1358258/full
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