Caffeine citrate increases ciliary beat frequency in human respiratory epithelial cells

Abstract Background Caffeine citrate is the gold-standard pharmacological treatment for apnea of prematurity, improving survival and long-term respiratory outcomes in preterm infants. Beyond its established central nervous system effects, emerging evidence suggests broader benefits in reducing extub...

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Hlavní autoři:	Sandra Cindrić, Laura Bodenbeck, Rim Hjeij, Niki Tomas Loges, Christine Edelbusch, Sebastian George, Petra Pennekamp, Esther Rieger-Fackeldey, Heymut Omran
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	SpringerOpen 2026-05-01
Edice:	Molecular and Cellular Pediatrics
Témata:	Caffeine citrate Bronchopulmonary dysplasia Neonates Ciliary beat frequency Air-liquid interface culture Mucociliary clearance
On-line přístup:	https://doi.org/10.1186/s40348-026-00239-y
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