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Ononin combined with Lactobacillus paracasei alleviates DSS-induced ulcerative colitis by ferroptosis via inhibiting JAK2/STAT3 signaling pathway

Background: Ulcerative colitis (UC) is a chronic inflammatory bowel disease with a complex pathogenesis and limited treatment options. This study aimed to evaluate the therapeutic effect of Ononin combined with Lactobacillus paracasei in a dextran sulfate sodium (DSS)-induced murine UC model and to...

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Principais autores: Mei Huang, Feng Yang, Ju-cai Song, Xue Wang, Pan-pan Jiao, Meng-jie Kang, Qian-qian Guo, Liang-zhu Si, Shu-han Zhang, Lin-shan Luo, Yong-wei Li, Wei Zhang, Yue-sheng Gong, Lei Dong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2026-03-01
coleção:Biochemistry and Biophysics Reports
Assuntos:
Ulcerative colitis
Ononin
Lactobacillus paracasei
Ferroptosis
JAK2/STAT3 pathway
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2405580826000427
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