Synthesis of functionalized tetrahydro-dispiro[pyrazolone 4, 2′-pyran-5′, 4″-pyrazolone] scaffolds via an Oxa-Michael-initiated cascade [4 + 2] annulation reaction using pyrazoledione-derived MBH-alcohols

In this study, an efficient protocol was developed for synthesizing tetrahydro-dispiro[pyrazolone 4, 2′-pyran-5′, 4″-pyrazolone] scaffolds, using pyrazoledione-derived MBH alcohols and arylidene pyrazolones. The reaction proceeds through an oxa-Michael-initiated cascade [4 + 2] annulation under meta...

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Detalhes bibliográficos

Principais autores:	Xiaoming Zhou, Juan Du, JiPeng Yuan, Xuehan Wang, Hongli Yang, Xuekun Wang, Zhenzhen Gao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2025-09-01
coleção:	Results in Chemistry
Assuntos:	[4 + 2] annulation Pyrazoledione-derived MBH alcohol Arylidene pyrazolones Tetrahydrodispiro[pyrazolone-pyran-pyrazolone]
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2211715625005879
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