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The role of distinct APOBEC/ADAR mRNA levels in mutational signatures linked to aging and ultraviolet radiation

Abstract The APOBEC/AID family is known for its mutator activity, and recent evidence also supports the potential impact of ADARs. Furthermore, the mutator impacts of APOBEC/ADAR mutations have not yet been investigated. Assessment of pancancer TCGA exomes identified enriched somatic variants among...

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Autor principal: Ahmadreza Niavarani
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Portfolio 2024-07-01
Colección:Scientific Reports
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Acceso en línea:https://doi.org/10.1038/s41598-024-64986-6
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