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Mixed pain: has pain medicine overlooked Its most common phenotype for over 20 years? A perspective on mechanistic interaction, the nociplastic paradox, and the future of pain classification

Pain medicine has progressively evolved from a binary classification of nociceptive and neuropathic pain toward a broader mechanistic framework that now includes nociplastic pain. While this evolution has substantially improved our understanding of chronic pain, it has not resolved a persistent clin...

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Principais autores: Rainer Freynhagen, Antonio Alcántara Montero
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2026-09-01
coleção:Frontiers in Medicine
Assuntos:
Acesso em linha:https://www.frontiersin.org/articles/10.3389/fmed.2026.1961489/full
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