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Influenza A Hemagglutinin Passage Bias Sites and Host Specificity Mutations

Animal studies aimed at understanding influenza virus mutations that change host specificity to adapt to replication in mammalian hosts are necessarily limited in sample numbers due to high cost and safety requirements. As a safe, higher-throughput alternative, we explore the possibility of using re...

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Principais autores: Raphael T. C. Lee, Hsiao-Han Chang, Colin A. Russell, Marc Lipsitch, Sebastian Maurer-Stroh
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2019-08-01
סדרה:Cells
נושאים:
influenza
passage
host specificity
mutations
adaptation
pandemic
hemagglutinin
גישה מקוונת:https://www.mdpi.com/2073-4409/8/9/958
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