PLA/Hydroxyapatite scaffolds exhibit in vitro immunological inertness and promote robust osteogenic differentiation of human mesenchymal stem cells without osteogenic stimuli

Abstract Bone defects stand out as one of the greatest challenges of reconstructive surgery. Fused deposition modelling (FDM) allows for the printing of 3D scaffolds tailored to the morphology and size of bone damage in a patient-specific and high-precision manner. However, FDM still suffers from th...

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Principais autores:	Marcela P. Bernardo, Bruna C. R. da Silva, Ahmed E. I. Hamouda, Marcelo A. S. de Toledo, Carmen Schalla, Stephan Rütten, Roman Goetzke, Luiz H. C. Mattoso, Martin Zenke, Antonio Sechi
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2022-02-01
coleção:	Scientific Reports
Acesso em linha:	https://doi.org/10.1038/s41598-022-05207-w
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