Circulating microbiome profiling in transjugular intrahepatic portosystemic shunt patients: 16S rRNA vs. shotgun sequencing

Background and aimCurrent efforts to characterize the circulating microbiome are constrained by the lack of standardized protocols for isolating and sequencing microbial communities in blood. To address this challenge, our study compared 16S rRNA (V3-V4 region) and shotgun metagenomic sequencing for...

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Κύριοι συγγραφείς:	Jingxiang Zhang, Xiaoshuang Xu, Lei Chen, Xincheng Yang, Júlio Ken Matsubara, Yuyao Tian, Jiahua Liu, Xiaoxu Jin, He Chang, Menghui Xu, Chunyang Zhu, Xin Wang, Lingxuan Ren, Jiale Xie, Jiale Liu, Guifen Liu, Mengyao Lu, Xiaowen Wang, Longqi Du, Zilin Ma, Xuechen Liu, Huimin Zhao, Wei Chen, Xiaohui Huo, Guoqi Zheng, Changshun Xie, Chao Xu, Xueqiang Zhang, Wei Qi, Zhijie Feng
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Frontiers Media S.A. 2025-12-01
Σειρά:	Frontiers in Medicine
Θέματα:	circulating microbiome TIPS shotgun sequencing 16S rRNA portal-hepatic circulation
Διαθέσιμο Online:	https://www.frontiersin.org/articles/10.3389/fmed.2025.1662837/full
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