Detection of HTLV-1 proviral DNA in cell-free DNA: Potential for non-invasive monitoring of Adult T cell leukaemia/lymphoma using liquid biopsy?

IntroductionFragmented genomic DNA is constitutively released from dying cells into interstitial fluid in healthy tissue. In cancer, this so-called ‘cell-free’ DNA (cfDNA) released from dying malignant cells encodes cancer-associated mutations. Thus, minimally invasive sampling of cfDNA in blood pla...

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Auteurs principaux:	Thomas Joris, Jana Haddow, Graham P. Taylor, Lucy B. M. Cook, Aileen G. Rowan
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2023-04-01
Collection:	Frontiers in Immunology
Sujets:	cell-free DNA liquid biopsy HTLV-1 adult T cell leukaemia/lymphoma provirus retrovirus
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1150285/full
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