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KEAP1 mutation in lung adenocarcinoma promotes immune evasion and immunotherapy resistance

Summary: Lung cancer treatment has benefited greatly through advancements in immunotherapies. However, immunotherapy often fails in patients with specific mutations like KEAP1, which are frequently found in lung adenocarcinoma. We established an antigenic lung cancer model and used it to explore how...

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Asıl Yazarlar: Anastasia-Maria Zavitsanou, Ray Pillai, Yuan Hao, Warren L. Wu, Eric Bartnicki, Triantafyllia Karakousi, Sahith Rajalingam, Alberto Herrera, Angeliki Karatza, Ali Rashidfarrokhi, Sabrina Solis, Metamia Ciampricotti, Anna H. Yeaton, Ellie Ivanova, Corrin A. Wohlhieter, Terkild B. Buus, Makiko Hayashi, Burcu Karadal-Ferrena, Harvey I. Pass, John T. Poirier, Charles M. Rudin, Kwok-Kin Wong, Andre L. Moreira, Kamal M. Khanna, Aristotelis Tsirigos, Thales Papagiannakopoulos, Sergei B. Koralov
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2023-11-01
Seri Bilgileri:Cell Reports
Konular:
CP: Cancer
CP: Immunology
Online Erişim:http://www.sciencedirect.com/science/article/pii/S2211124723013074
Etiketler: Etiketle
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