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Effects of Proline Substitutions on the Thermostable LOV Domain from <i>Chloroflexus aggregans</i>

Light-oxygen-voltage (LOV) domains are ubiquitous photosensory modules found in proteins from bacteria, archaea and eukaryotes. Engineered versions of LOV domains have found widespread use in fluorescence microscopy and optogenetics, with improved versions being continuously developed. Many of the e...

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Furkejuvvon:
Váldodahkkit: Alina Remeeva, Vera V. Nazarenko, Ivan M. Goncharov, Anna Yudenko, Anastasia Smolentseva, Oleg Semenov, Kirill Kovalev, Cansu Gülbahar, Ulrich Schwaneberg, Mehdi D. Davari, Valentin Gordeliy, Ivan Gushchin
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: MDPI AG 2020-03-01
Ráidu:Crystals
Fáttát:
fluorescent proteins
light-oxygen-voltage (LOV) domain
protein design
thermal stabilization
proline substitution
consensus design
Liŋkkat:https://www.mdpi.com/2073-4352/10/4/256
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