Fruquintinib potentiates the radiosensitivity of colorectal cancer by exacerbating DNA damage

Abstract Objective To investigate the radiosensitizing effect of fruquintinib, a vascular endothelial growth factor receptor (VEGFR) inhibitor, on colorectal cancer (CRC), and to determine whether this effect is mediated not only through anti-angiogenic activity but also via direct cellular mechanis...

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Detalhes bibliográficos

Principais autores:	Qian Shen, Danwei Wang, Yang Zhao, Zeyuan Hao, Ruiyuan Zhang, Deqian Song, Aimin Tang, Guoliang Yao, Qian Han
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-02-01
coleção:	European Journal of Medical Research
Assuntos:	Colorectal cancer Fruquintinib Irradiation Radiosensitization
Acesso em linha:	https://doi.org/10.1186/s40001-026-04075-8
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