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Micromass co-culture of human articular chondrocytes and human bone marrow mesenchymal stem cells to investigate stable neocartilage tissue formation in vitro

Cell therapies for articular cartilage defects rely on expanded chondrocytes. Mesenchymal stem cells (MSC) represent an alternative cell source should their hypertrophic differentiation pathway be prevented. Possible cellular instruction between human articular chondrocytes (HAC) and human bone marr...

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Autors principals: S Giovannini, J Diaz-Romero, T Aigner, P Heini, P Mainil-Varlet, D Nesic
Format: Artigo
Idioma:Inglês
Publicat: Forum Multimedia Publishing LLC 2010-10-01
Col·lecció:European Cells & Materials
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Accés en línia:http://www.ecmjournal.org/journal/papers/vol020/pdf/v020a20.pdf
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