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Intestinal Microfold Cells Play a Critical Role in the Uptake and Oral Tolerance Mediated by Lysophosphatidylserine-Containing Lipidic Nanoparticles

Phosphatidylserine (PS) is an anionic phospholipid that is exposed to the outer leaflet of the cell membrane during apoptosis. This PS externalization can teach the immune system to tolerate an antigen without eliciting immunological consequences. Previously, we showed that mice treated with PS nano...

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Principais autores: Vincent Chak, Sujay Harne, Jason G. Kay, Elizabeth Wohlfert, Sathy V. Balu-Iyer
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2026-03-01
Series:Nanomaterials
Assuntos:
phosphatidylserine
nanoparticle
oral tolerance
apoptosis
regulatory T cells
immune regulation
Acceso en liña:https://www.mdpi.com/2079-4991/16/7/412
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