Application of CIBERSORTx and BayesPrism to deconvolution of bulk RNA-seq data from human myocardium and skeletal muscle

RNA-sequencing (RNA-seq) is an important tool to explore molecular mechanisms of disease. Technological advances mean this can be performed at the single-cell level, but the large sample sizes needed in clinical studies are currently prohibitively expensive and complex. Deconvolution of bulk RNA-seq...

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Hauptverfasser:	Marcella Conning-Rowland, Chew W. Cheng, Oliver Brown, Marilena Giannoudi, Eylem Levelt, Lee D. Roberts, Kathryn J. Griffin, Richard M. Cubbon
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2025-02-01
Schriftenreihe:	Heliyon
Schlagworte:	RNA-Seq Deconvolution Myocardium Skeletal muscle Age Sex
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2405844025008795
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