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microRNA-194 is increased in polycystic ovary syndrome granulosa cell and induce KGN cells apoptosis by direct targeting heparin-binding EGF-like growth factor

Abstract Background Polycystic ovary syndrome (PCOS) is an endocrine-related follicular developmental disorder that affects 50 %-70 % of reproductive-aged women diagnosed with ovulation-related infertility. Abnormal proliferation and apoptosis of granulosa cells (GCs) are thought to be the critical...

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Autori principali: Yi-xuan Wu, Yan-shan Lin, Si-chen Li, Xi Yao, Mingwei Cheng, Lin Zhu, Hai-ying Liu
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2021-11-01
Serie:Reproductive Biology and Endocrinology
Soggetti:
miRNA
Cell growth
Granulosa cells
PCOS
Accesso online:https://doi.org/10.1186/s12958-021-00850-w
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