Identification and impact on Pseudomonas aeruginosa virulence of mutations conferring resistance to a phage cocktail for phage therapy

ABSTRACT Phage therapy represents a promising strategy for curing bacterial infections refractory to antibiotics. However, the success rate of phage therapy may be lowered by the emergence of bacterial resistance to the phages used for therapy. In this work, we studied the resistance to the CK4 cock...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Francesca Forti, Claudia Bertoli, Marco Cafora, Sara Gilardi, Anna Pistocchi, Federica Briani
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology 2023-12-01
Schriftenreihe:	Microbiology Spectrum
Schlagworte:	bacteriophage therapy phage receptors Pseudomonas aeruginosa phages zebrafish infection model
Online-Zugang:	https://journals.asm.org/doi/10.1128/spectrum.01477-23
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