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Development and validation of a nomogram model for predicting negative/indeterminate HIV-1 antibody confirmation: a strategy to streamline the diagnostic pathway

Abstract Background The standard HIV diagnostic algorithm comprises sequential serological screening, confirmatory antibody testing, and nucleic acid confirmation when necessary. This multi-step process often causes diagnostic delays, particularly in cases with indeterminate or discordant results. D...

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Principais autores: Guijuan Liao, Shaocheng Zhang, Yi Wei, Yu Jin, Xiaoling Liu, Hui Quan, Huanhuan Wang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2026-05-01
Serier:BMC Medical Informatics and Decision Making
Fag:
HIV diagnosis
Nomogram
Predictive model
Western blot
Nucleic acid testing
Diagnostic algorithm
Online adgang:https://doi.org/10.1186/s12911-026-03546-6
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