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Failure of homologous synapsis and sex-specific reproduction problems

The prophase of meiosis I ensures the correct segregation of chromosomes to each daughter cell. This includes the pairing, synapsis and recombination of homologous chromosomes. A subset of chromosomal abnormalities, including translocation and inversion, disturbs these processes, resulting in the fa...

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Huvudupphov: Hiroki eKurahashi, Hiroshi eKogo, Makiko eTsutsumi, Hidehito eInagaki, Tamae eOhye
Materialtyp: Artigo
Språk:Inglês
Utgiven: Frontiers Media S.A. 2012-06-01
Serie:Frontiers in Genetics
Ämnen:
Infertility
translocation
sex body
meiotic sex chromosome silencing
meiotic silencing of unsynapsed chromosomes
Hormad1
Länkar:http://journal.frontiersin.org/Journal/10.3389/fgene.2012.00112/full
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