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Borna disease virus docks on neuronal DNA double-strand breaks to replicate and dampens neuronal activity

Summary: Borna disease viruses (BoDV) have recently emerged as zoonotic neurotropic pathogens. These persistent RNA viruses assemble nuclear replication centers (vSPOT) in close interaction with the host chromatin. However, the topology of this interaction and its consequences on neuronal function r...

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Bibliografiske detaljer
Principais autores: Florent Henri Marty, Luca Bettamin, Anne Thouard, Karine Bourgade, Sophie Allart, Guilhem Larrieu, Cécile Evelyne Malnou, Daniel Gonzalez-Dunia, Elsa Suberbielle
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2022-01-01
Serier:iScience
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Online adgang:http://www.sciencedirect.com/science/article/pii/S2589004221015911
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