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Synthesis, Biocidal and Antibiofilm Activities of New Isatin–Quinoline Conjugates against Multidrug-Resistant Bacterial Pathogens along with Their In Silico Screening

Isatin–quinoline conjugates <b>10a</b>–<b>f</b> and <b>11a</b>–<b>f</b> were assembled by the reaction of N-(bromobutyl) isatin derivatives <b>3a</b>, <b>b</b> with aminoquinolines <b>6a</b>–<b>c</b> and their corresponding hydrazinyl <b>9a</b>–<b>c</b> in good yields. The structures of the resultin...

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Principais autores: Elshaymaa I. Elmongy, Abdullah A. S. Ahmed, Ibrahim El Tantawy El Sayed, Ghady Fathy, Hanem M. Awad, Ayah Usama Salman, Mohamed A. Hamed
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2022-10-01
Serier:Antibiotics
Fag:
isatin
aminoquinoline
conjugates
bactericidal activity
antibiofilm
TEM
Online adgang:https://www.mdpi.com/2079-6382/11/11/1507
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