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Integrated Process for Capture and Purification of Virus-Like Particles: Enhancing Process Performance by Cross-Flow Filtration

Virus-like particles (VLPs) are emerging nanoscale protein assemblies applied as prophylactic vaccines and in development as therapeutic vaccines or cargo delivery systems. Downstream processing (DSP) of VLPs comes both with challenges and opportunities, depending on the complexity and size of the s...

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主要な著者: Nils Hillebrandt, Philipp Vormittag, Nicolai Bluthardt, Annabelle Dietrich, Jürgen Hubbuch
フォーマット: Artigo
言語:Inglês
出版事項: Frontiers Media S.A. 2020-05-01
シリーズ:Frontiers in Bioengineering and Biotechnology
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オンライン・アクセス:https://www.frontiersin.org/article/10.3389/fbioe.2020.00489/full
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