Simultaneous Increases in Intracellular Sodium and Tonicity Boost Antimicrobial Activity of Macrophages

Inflamed and infected tissues can display increased local sodium (Na⁺) levels, which can have various effects on immune cells. In macrophages, high salt (HS) leads to a Na⁺/Ca²⁺-exchanger 1 (NCX1)-dependent increase in intracellular Na⁺ levels. This result...

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Autors principals:	Luka Krampert, Thomas Ossner, Agnes Schröder, Valentin Schatz, Jonathan Jantsch
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2023-12-01
Col·lecció:	Cells
Matèries:	macrophages Na<sup>+</sup>/K<sup>+</sup>-ATPase cardiac glycosides sodium intracellular sodium osmotic stress
Accés en línia:	https://www.mdpi.com/2073-4409/12/24/2816
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