Novel Alzheimer’s disease genes and epistasis identified using machine learning GWAS platform

Abstract Alzheimer’s disease (AD) is a complex genetic disease, and variants identified through genome-wide association studies (GWAS) explain only part of its heritability. Epistasis has been proposed as a major contributor to this ‘missing heritability’, however, many current methods are limited t...

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Bibliografische Detailangaben

Hauptverfasser:	Mischa Lundberg, Letitia M. F. Sng, Piotr Szul, Rob Dunne, Arash Bayat, Samantha C. Burnham, Denis C. Bauer, Natalie A. Twine
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2023-10-01
Schriftenreihe:	Scientific Reports
Online-Zugang:	https://doi.org/10.1038/s41598-023-44378-y
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