A complex interplay between H2A.Z and HP1 isoforms regulates pericentric heterochromatin

Pericentric heterochromatin (PCH) plays an essential role in the maintenance of genome integrity and alterations in PCH have been linked to cancer and aging. HP1 α, β, and γ, are hallmarks of constitutive heterochromatin that are thought to promote PCH structure through binding to heterochromatin-sp...

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Bibliografiske detaljer

Principais autores:	Jessica González, Laia Bosch-Presegué, Anna Marazuela-Duque, Anna Guitart-Solanes, María Espinosa-Alcantud, Agustín F. Fernandez, Jeremy P. Brown, Juan Ausió, Berta N. Vazquez, Prim B. Singh, Mario F. Fraga, Alejandro Vaquero
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2023-11-01
Serier:	Frontiers in Cell and Developmental Biology
Fag:	HP1α,β,γ heterochromatin H2A.Z epigenetics genome stability H3K9me3
Online adgang:	https://www.frontiersin.org/articles/10.3389/fcell.2023.1293122/full
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