Targeting endothelial cells: the pathological mechanisms and therapeutic innovations in pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH) is a fatal disease with high mortality, which is characterized by pulmonary vascular remodeling. Current clinical treatments mainly focus on dilating vascular and relieving pulmonary artery pressure. However, there is still no effective treatment available to re...

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Bibliografische Detailangaben

Hauptverfasser:	Tianfei Fan, Longji Li, Yao Wang, Meng Lin, Fengbo Wu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2025-11-01
Schriftenreihe:	Frontiers in Cell and Developmental Biology
Schlagworte:	pulmonary arterial hypertension endothelial cells endothelial-mesenchymal transition crosstalk stem cell treatment
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fcell.2025.1690124/full
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