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Zinc and Copper Ions Differentially Regulate Prion-Like Phase Separation Dynamics of Pan-Virus Nucleocapsid Biomolecular Condensates

Liquid-liquid phase separation (LLPS) is a rapidly growing research focus due to numerous demonstrations that many cellular proteins phase-separate to form biomolecular condensates (BMCs) that nucleate membraneless organelles (MLOs). A growing repertoire of mechanisms supporting BMC formation, compo...

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Principais autores: Anne Monette, Andrew J. Mouland
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2020-10-01
Serier:Viruses
Fag:
nucleocapsid protein
pan-virus
retrovirus
viral genomic RNA
liquid-liquid phase separation
biomolecular condensate
Online adgang:https://www.mdpi.com/1999-4915/12/10/1179
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