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Taperin (c9orf75), a mutated gene in nonsyndromic deafness, encodes a vertebrate specific, nuclear localized protein phosphatase one alpha (PP1α) docking protein

Summary The promiscuous activity of protein phosphatase one (PP1) is controlled in the cell by associated proteins termed regulatory or targeting subunits. Using biochemical and proteomic approaches we demonstrate that the autosomal recessive nonsyndromic hearing loss gene, taperin (C9orf75), encode...

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Bibliografiset tiedot
Päätekijät: Tony Ferrar, Delphine Chamousset, Veerle De Wever, Mhairi Nimick, Jens Andersen, Laura Trinkle-Mulcahy, Greg B. G. Moorhead
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Company of Biologists 2012-02-01
Sarja:Biology Open
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Linkit:http://bio.biologists.org/content/1/2/128
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