Hippo signaling pathway regulates Ebola virus transcription and egress
Abstract Filovirus-host interactions play important roles in all stages of the virus lifecycle. Here, we identify LATS1/2 kinases and YAP, key components of the Hippo pathway, as critical regulators of EBOV transcription and egress. Specifically, we find that when YAP is phosphorylated by LATS1/2, i...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Portfolio
2024-08-01
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| Serie: | Nature Communications |
| Accesso online: | https://doi.org/10.1038/s41467-024-51356-z |
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