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Targeting endoplasmic reticulum stress: an innovative therapeutic strategy for podocyte-related kidney diseases

Abstract The endoplasmic reticulum (ER) is a vital organelle responsible for protein quality control, including the folding, modification, and transport of proteins. When misfolded or unfolded proteins accumulate in the ER, it triggers endoplasmic reticulum stress (ERS) and activates the unfolded pr...

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主要な著者: Jiao Lv, Honghai Yu, Sasa Du, Pengyu Xu, Yunyun Zhao, Wenxiu Qi, Xiuge Wang
フォーマット: Artigo
言語:Inglês
出版事項: BMC 2025-01-01
シリーズ:Journal of Translational Medicine
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オンライン・アクセス:https://doi.org/10.1186/s12967-025-06076-3
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