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Mesenchymal stem cell-derived exosomes promote scalp rejuvenation through type XVII collagen regulation via the miR-21-5p/DKK2/Wnt pathway

BackgroundHair follicle aging is driven by COL17A1 proteolysis in hair follicle stem cells (HFSCs). Mesenchymal stem cell (MSC)-derived exosomes show promise in tissue regeneration, but their effects on COL17A1 and hair follicle aging remain unexplored.MethodsExosomes isolated from human umbilical c...

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Hlavní autoři: Shiyue Cui, Yuanyuan Huang, Duo Zeng, Jie Li, Chun Tang
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2026-04-01
Edice:Frontiers in Cell and Developmental Biology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fcell.2026.1807877/full
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