Widespread macrolide resistance among rapidly growing mycobacteria due to plasmids containing erm(55)

Abstract Macrolides (clarithromycin and azithromycin) are a mainstay of therapy for infections caused by rapidly growing mycobacteria (RGM). Historically, macrolide resistance in RGM species is associated with mutations in the 23S rRNA gene and chromosomal erythromycin ribosome methylase (erm) genes...

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Hlavní autoři:	Christopher I. Graham, Barbara A. Brown-Elliott, Bibiana Gonzalez-Ramirez, Kavya Somayaji, Stephanie Melton, Michelle Wuzinski, Nancy L. Wengenack, Richard J. Wallace, David C. Alexander
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2026-01-01
Edice:	Scientific Reports
Témata:	Mycobacteria Antimicrobial resistance Plasmid
On-line přístup:	https://doi.org/10.1038/s41598-025-32174-9
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