Mechanical Stretch‐Induced Interlayer Coordination between MMP2 and COL17A1 Exacerbates Regenerative Exhaustion in Skin

Abstract The layered structure of skin necessitates highly sophisticated tissue coordination during regeneration. The unmet clinical need of long‐term skin expansion therapy stems from limited regenerative capacity, yet the underlying mechanism remains enigmatic due to the lack of appropriate animal...

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Detalhes bibliográficos

Principais autores:	Yidan Sun, Qili Qian, Luwen Xu, Bowen Gao, Ting Li, Yin Li, Jiayi Zheng, Qiaoyu Fu, Xi Cheng, Nuo Chen, Sijia Wang, Liang Zhang, Caiyue Liu, Qingfeng Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2025-11-01
Colecção:	Advanced Science
Assuntos:	COL17A1 proteolysis ECM turnover marimastat MMP2 regenerative exhaustion
Acesso em linha:	https://doi.org/10.1002/advs.202511474
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