Clinical, Immunological, and Molecular Findings in Four Cases of B Cell Expansion With NF-κB and T Cell Anergy Disease for the First Time From India

B cell expansion with NF-κB and T cell anergy (BENTA) is a rare primary immunodeficiency disorder caused by mutations in the CARD11 gene and results in constitutive NF-κB activation in B and T cells. Affected patients present with polyclonal expansion of B cells at an early age with splenomegaly, ly...

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Główni autorzy:	Maya Gupta, Jahnavi Aluri, Mukesh Desai, Madhukar Lokeshwar, Prasad Taur, Michael Lenardo, Jenna Bergerson, Aparna Dalvi, Snehal Mhatre, Manasi Kulkarni, Priyanka Kambli, Manisha Madkaikar
Format:	Artigo
Język:	Inglês
Wydane:	Frontiers Media S.A. 2018-06-01
Seria:	Frontiers in Immunology
Hasła przedmiotowe:	CARD11 polyclonal B cell lymphocytosis NF-κB GOF mutation autoimmune lymphoproliferative syndrome
Dostęp online:	https://www.frontiersin.org/article/10.3389/fimmu.2018.01049/full
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