Predicting the diagnostic efficacy of trio-based whole exome sequencing in children with low-function autism spectrum disorders: a multicenter study

BackgroundAlthough significant progress has been made in trio-based whole-exome sequencing (trio-WES) that enables the detection of exon-level variants, the diagnostic effectiveness of empirical and unselected use of trio-WES in children with low-function autism spectrum disorders (LF-ASDs) remains...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Ruohao Wu, Xiangyang Luo, Zhanwen He, Zhe Meng, Wenting Tang, Liyang Liang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-10-01
coleção:	Frontiers in Neurology
Assuntos:	low-function autism spectrum disorders neurodevelopmental/neurological comorbidities trio-based whole-exome sequencing diagnostic rate phenotype-driven nomogram
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fneur.2025.1597588/full
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!