Thrombin-Derived Host-Defense Peptides Modulate Monocyte/Macrophage Inflammatory Responses to Gram-Negative Bacteria

Host-defense peptides play a fundamental role in the innate immune system by modulating inflammatory responses. Previously, it was shown that the thrombin derived host-defense peptide GKY25 inhibits LPS-induced responses of monocytes and macrophages in vitro, ex vivo, and in vivo. In this study, the...

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Autors principals:	Finja C. Hansen, Ann-Charlotte Strömdahl, Matthias Mörgelin, Artur Schmidtchen, Mariena J. A. van der Plas
Format:	Artigo
Idioma:	Inglês
Publicat:	Frontiers Media S.A. 2017-07-01
Col·lecció:	Frontiers in Immunology
Matèries:	host-defense peptides Gram-negative bacteria monocytes macrophages thrombin phagocytosis
Accés en línia:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.00843/full
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