Silibinin Downregulates the NF-κB Pathway and NLRP1/NLRP3 Inflammasomes in Monocytes from Pregnant Women with Preeclampsia

Preeclampsia (PE) is a human pregnancy-specific syndrome with abnormal activation of cells from the innate immune system. The present study evaluated whether silibinin (SB) treatment of monocytes from preeclamptic women could modulate NLRP1 and NLRP3 inflammasomes as well as TLR4/NF-κB pathway...

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Autors principals:	Mariana Leticia Matias, Virginia Juliani Gomes, Mariana Romao-Veiga, Vanessa Rocha Ribeiro, Priscila Rezeck Nunes, Graziela Gorete Romagnoli, Jose Carlos Peracoli, Maria Terezinha Serrao Peracoli
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2019-04-01
Col·lecció:	Molecules
Matèries:	NLRP1/NLRP3 inflammasomes NF-κB monocytes monosodium urate preeclampsia silibinin
Accés en línia:	https://www.mdpi.com/1420-3049/24/8/1548
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