Pax6 mutant cerebral organoids partially recapitulate phenotypes of Pax6 mutant mouse strains
Cerebral organoids show great promise as tools to unravel the complex mechanisms by which the mammalian brain develops during embryogenesis. We generated mouse cerebral organoids harbouring constitutive or conditional mutations in Pax6, which encodes a transcription factor with multiple important ro...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Public Library of Science (PLoS)
2022-01-01
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| Series: | PLoS ONE |
| Acceso en liña: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9704552/?tool=EBI |
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