Interleukin-24 inhibits the phenotype and tumorigenicity of cancer stem cell in osteosarcoma via downregulation Notch and Wnt/β-catenin signaling

Osteosarcoma frequently presents as recurrence and metastasis, even if the primary lesion was eradicated and/or radiotherapy and chemotherapy were administered. Osteosarcoma cancer stem cells (CSCs) are one of the key factors for the recurrence and metastasis of osteosarcoma. We have shown that inte...

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Bibliografische Detailangaben

Hauptverfasser:	Baobiao Zhuo, Xihua Wang, Yang Shen, Jiayong Li, Shixian Li, Yuan Li, Rong Wang
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2021-12-01
Schriftenreihe:	Journal of Bone Oncology
Schlagworte:	IL-24 Cancer stem cell Osteosarcoma Notch signaling Wnt/β-catenin signaling
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2212137421000580
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