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A single residue in the yellow fever virus envelope protein modulates virion architecture and antigenicity

Abstract Yellow fever virus (YFV) is a re-emerging flavivirus that causes severe hepatic disease and mortality in humans. Despite being researched for over a century, the structure of YFV has remained elusive. Here we use a chimeric virus platform to resolve the first high resolution cryo-EM structu...

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Hlavní autoři: Summa Bibby, James Jung, Yu Shang Low, Alberto A. Amarilla, Natalee D. Newton, Connor A. P. Scott, Jessica Balk, Yi Tian Ting, Morgan E. Freney, Benjamin Liang, Timothy Grant, Fasséli Coulibaly, Paul Young, Roy A. Hall, Jody Hobson-Peters, Naphak Modhiran, Daniel Watterson
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2025-09-01
Edice:Nature Communications
On-line přístup:https://doi.org/10.1038/s41467-025-63038-5
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