Psychological and quality of life outcomes associated with multikinase inhibitors versus immune checkpoint inhibitors in advanced hepatocellular carcinoma

Abstract To compare the effects of multikinase inhibitors (sorafenib/lenvatinib) and immune checkpoint inhibitors (PD-1/PD-L1) on anxiety, depression, and quality of life (QoL) in patients with advanced hepatocellular carcinoma (HCC) and to analyse their correlations with clinical indicators. This r...

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Detalhes bibliográficos

Principais autores:	Maher Hendi, Jie-Min Lv, Mohamad Hndi, Bin Zhang, Xue-Qin Chen, Ying-Ying Chen, Yu Pan, Xiu-Jun Cai
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Portfolio 2026-02-01
coleção:	Scientific Reports
Assuntos:	Hepatocellular carcinoma Multikinase inhibitors Immune checkpoint inhibitors Anxiety Depression
Acesso em linha:	https://doi.org/10.1038/s41598-026-39864-y
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