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Characterization of a peptide domain within the GB virus C NS5A phosphoprotein that inhibits HIV replication.

BACKGROUND:GBV-C infection is associated with prolonged survival in HIV-infected people and GBV-C inhibits HIV replication in co-infection models. Expression of the GBV-C nonstructural phosphoprotein 5A (NS5A) decreases surface levels of the HIV co-receptor CXCR4, induces the release of SDF-1 and in...

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-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Jinhua Xiang, James H McLinden, Qing Chang, Emma L Jordan, Jack T Stapleton
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Public Library of Science (PLoS) 2008-07-01
Цуврал:PLoS ONE
Онлайн хандалт:http://europepmc.org/articles/PMC2440355?pdf=render
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