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Macrophages Are Dispensable for Postnatal Pruning of the Cochlear Ribbon Synapses

Ribbon synapses of cochlear hair cells undergo pruning and maturation before the hearing onset. In the central nervous system (CNS), synaptic pruning was mediated by microglia, the brain-resident macrophages, via activation of the complement system. Whether a similar mechanism regulates ribbon synap...

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Autori principali: Chaorong Yu, Hui-Ming Gao, Guoqiang Wan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2021-10-01
Serie:Frontiers in Cellular Neuroscience
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Accesso online:https://www.frontiersin.org/articles/10.3389/fncel.2021.736120/full
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